Colon Cancer

Reports outline colon cancer study results from L.M. Veenendaal et al

Published in Cancer Weekly, April 8th, 2008

"Loss of epithelial morphology and the acquisition of mesenchymal characteristics may contribute to metastasis formation during colorectal tumorigenesis. The Wnt, Notch and TGF beta signaling pathways control tissue homeostasis and tumor development in the gut," scientists writing in the journal Cellular Oncology report.

"The relationship between the activity of these pathways and the expression of epithelial and mesenchymal markers was investigated in a series of primary colorectal tumors and their corresponding metastases. Tissue samples of primary colorectal tumors, normal colonic mucosa, and regional and systemic metastases were processed for...

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Source: Cancer Weekly (2008-04-08)

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