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Cancer Weekly

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Cancer Vaccines



Scientists at University of North Carolina detail research in cancer vaccines



April 8th, 2008

Researchers detail in 'A simple but effective cancer vaccine consisting of an antigen and a cationic lipid,' new data in cancer. According to recent research from the United States, "Developing a cancer vaccine with a potent adjuvant, which is safe for human use, remains to be an unmet need. In this study, we developed a simple, safe, yet efficient, peptide-based therapeutic cancer vaccine, DOTAP/E7 complex, which comprises only two molecules: a DOTAP cationic lipid and a peptide antigen derived from E7 oncoprotein of human papillomavirus (HPV) type 16."

"The anti-cancer activity of DOTAP/E7 against existing HPV positive TC-1 tumor was compared to that of our previous...


Source: Cancer Weekly (2008-04-08)

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