Cancer Weekly
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Angiogenesis
New findings in angiogenesis described from Louisiana State University
April 8th, 2008
According to a study from the United States, "This study examines the target specificity of tetrathiomolybdate (ATM), an anti-angiogenic, antitumor agent against the viability / proliferation of arterial, venous, capillary endothelial and tumor cells. Cells were seeded at 10 or 100% density (to measure viability / proliferation respectively) in medium +/- 0-250uM ATM." "Viability and proliferation were measured by metabolic labeling-colorimetry. One-way ANOVA + Bonferroni testing examined base metabolism; Dunnett's testing was used for viability/proliferation. Venous proliferation showed high ATM sensitivity (50% reduction similar to >= 5uM ATM, p<0.01), capillary...
Source: Cancer Weekly (2008-04-08)
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