Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Apoptosis
Research on apoptosis detailed by scientists at Virginia Commonwealth University
April 8th, 2008
According to recent research from the United States, "Apoptosis is a major mechanism of gastric cell death induced by deoxycholate (DC) and aspirin (ASA), and the caspase cascade and protein kinase C (PKC) signaling play key roles in this process. The transcription factor kappa B (NF-kappa B) has been shown to modulate apoptosis by regulating the transcription of numerous pro- and anti-apoptotic genes." "The aim of this study was to investigate the effect of DC and ASA on NF-kappa B signaling, and determine its role in programmed cell death in a human gastric carcinoma cell line. Cells were incubated with DC in the presence or absence of ASA or proteasome inhibitors...
Source: Cancer Weekly (2008-04-08)
|
