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Cancer Weekly

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Bladder Cancer



Data from University of Oklahoma, Medical Department advance knowledge in bladder cancer



April 8th, 2008

According to a study from the United States, "The lymphatics form a second circulatory system that drains the extracellular fluid and proteins from the tumor microenvironment, and provides an exclusive environment in which immune cells interact and respond to foreign antigen. Both cancer and inflammation are known to induce lymphangiogenesis."

"However, little is known about bladder lymphatic vessels and their involvement in cancer formation and progression. A double transgenic mouse model was generated by crossing a bladder cancer-induced transgenic, in which SV40 large T antigen was under the control of uroplakin II promoter, with another transgenic mouse harboring a...


Source: Cancer Weekly (2008-04-08)

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