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Cancer Gene Therapy
Researchers at Southeast University, Department of Clinical Medicine target cancer gene therapy
April 15th, 2008
Scientists discuss in 'Inhibition of DLC-1 gene expression by RNA interference in the colon cancer LoVo cell line' new findings in cancer gene therapy. "DLC-1 (deleted in liver cancer-1) is a potential tumor suppressor gene, which is inactive in liver carcinogenesis. To observe the effects of DLC-1 gene expression on cell proliferation and migration in the human colon cancer cell line, RNAi Lipo-recombinant of the DLC-1 gene (pGCsil-DLC-1) was constructed and transduced into LoVo cells which are positive for DLC-1 gene expression," scientists writing in the journal Oncology Reports report. "Results showed that the RNAi recombinant effectively inhibited the...
Source: Cancer Weekly (2008-04-15)
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