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Vaccines
Research on vaccines published by scientists at General Hospital, Department of Hematology
April 15th, 2008
Fresh data on vaccines are presented in the report 'Enhanced protein expression by internal ribosomal entry site-driven mRNA translation as a novel approach for in vitro loading of dendritic cells with antigens.' According to a study from Beijing, People's Republic of China, "Transfection of dendritic cells (DCs) with messenger RNAs (mRNAs) of tumor-associated antigens (TAAs) is a promising strategy for cancer vaccines. TAA mRNA can be generated by in vitro transcription using DNA encoding the TAA gene as a template." "A cap analog is usually added upon in vitro transcription to stabilize mRNA and enhance the efficiency of mRNA translation. However, the inclusion of the...
Source: Cancer Weekly (2008-04-15)
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