Cancer Weekly
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Apoptosis
Data from B. Lankatbuttgereit and colleagues advance knowledge in apoptosis
April 15th, 2008
"Pdcd4 (programmed cell death protein 4) was identified as a gene up-regulated during apoptosis and, additionally, seems to have a function as a tumor suppressor. However, there are conflicting data concerning its role in programmed cell death and most results for its action as an inhibitor for neoplastic transformation are derived from experiments with epidermal cells," scientists writing in the journal Apoptosis report. "Therefore, we were interested to investigate if the action of Pdcd4 might be cell type specific. For that purpose we examined the expression of Pdcd4 and several other proteins in various tumor cell lines. We could not find any correlation of...
Source: Cancer Weekly (2008-04-15)
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