Cancer Weekly
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Cancer Gene Therapy
New cancer gene therapy findings from Y.M. Li and co-authors described
April 22nd, 2008
In this recently published article, scientists in Shanghai, People's Republic of China conducted a study "To evaluate the therapeutic efficiency of replicative adenovirus CNHK300 targeted in telomerase-positive hepatocellular carcinoma. CNHK300, ONYX-015 (55 kDa protein deleted adenovirus) and wtAd5 (wild type adenovirus 5) were compared, and virus proliferation assay, cell viability assay, Western blot and fluorescence microscopy were used to evaluate the proliferation and cytolysis selectivity of CNHK300." "The replicative multiples in Hep3B and HepG H after 48 h of CNHK300 proliferation were 40625 and 65326 fold, respectively, similar to that of wtAd5.. However,...
Source: Cancer Weekly (2008-04-22)
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