Cancer Weekly
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Astrocytoma
Researchers at Kitasato University target astrocytoma
April 22nd, 2008
According to recent research from Kanagawa, Japan, "Definitive distinction between low-grade astrocytoma and astrogliosis is a long-standing difficulty due to their similar histopathological characteristics. To clarify differences in biological significance, this study focused on various components of the cell cycle machinery and proliferation as key parameters, comparing expression in astrogliosis, as well as low- and high-grade astrocytomas." "The expression of p16, p21 and p27, and cyclin A, cyclin D1, cyclin E, Rb and Ki-67 was immunohistochemically examined in 40 cases of astrogliosis and 48 cases of low- grade astrocytomas (grade II), as well as 50 high-grade...
Source: Cancer Weekly (2008-04-22)
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