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Barrett Esophagus
Researchers' work from University of Erlangen focuses on barrett esophagus
April 22nd, 2008
According to recent research from Erlangen, Germany, " Obesity is an important risk factor for Barrett adenocarcinoma. However, the role of adiponectin (anti-inflammatory adipokine from adipose tissue) and ghrelin (orexigenic peptide gastric origin) on the progression of Barrett's carcinogenesis has not been investigated so far." "The aim of the present study was: (1) to compare the expression of adiponectin and ghrelin receptors in Barrett's esophagus and in normal squamous epithelium; (2) to assess the effect of adiponectin and ghrelin on apoptosis in Barrett's adenocarcinoma cells in vitro; and (3) to investigate the effect of ghrelin on IL-1 beta and COX-2...
Source: Cancer Weekly (2008-04-22)
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