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Cancer Weekly

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Cancer Vaccines



New cancer vaccines research from University of Kiel outlined



April 22nd, 2008

According to recent research published in the International Journal of Oncology, "Overexpression of lysyl oxidase (LOX) is associated with the invasive potential of metastatic breast and head and neck cancer (HNC) cells and reduced metastasis-free and overall survival. Recently, we have demonstrated up-regulation of a new member of the LOX family, lysyl oxidase-like 4 (LOXL4), in invasive HNC revealed a significant correlation between LOXL4 expression and local lymph node metastases and higher tumour stages."

"The objective of this study was to examine whether cellular LOXL4 may provide an effective target for cell-meditated immunotherapy in invasive tumours...


Source: Cancer Weekly (2008-04-22)

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