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Oral Squamous Cell Carcinoma

Research from Chung-Shan Medical University, Institute of Medicine in oral squamous cell carcinoma provides new insights

Published in Cancer Weekly, April 22nd, 2008

Research findings, 'The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas,' are discussed in a new report. According to a study from Taichung, Taiwan, "Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich, inducible, intracellular proteins that bind heavy metals with high affinity. MT-1 is known as a stress-inducible protein and functions as an antioxidant enzyme."

"Areca quid chewing is a major risk factor in the development and further progression of oral squamous cell carcinoma (OSCC). The aim of this study was to compare MT-1 expression in normal human oral epithelium and OSCC and...

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