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Cancer Gene Therapy
New cancer gene therapy research from National Institutes of Health outlined
April 29th, 2008
A report, 'Parathyroid tumor development involves deregulation of homeobox genes,' is newly published data in Endocrine-related Cancer. "Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome caused by mutations in the MEN1 tumor suppressor gene. Loss of the functional second copy of the MEN1 gene causes individuals to develop multiple endocrine tumors, primarily affecting the parathyroid, pituitary, and pancreas," investigators in the United States report. "While it is clear that the protein encoded by MEN1, menin, suppresses endocrine tumors, its biochemical functions and direct downstream targets remain unclear. Recent studies have...
Source: Cancer Weekly (2008-04-29)
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