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Cancer Weekly

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Hormones



Findings from V. Costa and co-authors provide new insights into hormones



April 29th, 2008

Researchers detail in 'The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists,' new data in hormones. "The peroxisome proliferator-activated receptor-gamma (PPARgamma) is a member of the nuclear hormone receptor superfamily. Ligand activation of PPARgamma is associated with differentiation and inhibition of proliferation in the normal and malignant cells," scientists in Italy report.

"Herein, we studied the effects of PPARgamma and the PPARgamma agonists thiazolidinediones (TZDs) on the insulin receptor (IR), a cell membrane tyrosine kinase receptor protein, whose role is of...


Source: Cancer Weekly (2008-04-29)

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