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Cancer Weekly

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Acute Myeloid Leukemia



Studies from University of Tsukuba, Medical Department provide new data on acute myeloid leukemia



April 29th, 2008

" To evaluate a less intensive chemotherapeutic regimen specifically designed for patients with Down syndrome (DS) and acute myeloid leukemia (AML), and to determine the prognostic factors for event-free survival. Patients and Methods Seventy-two patients with AML-DS were treated with remission induction chemotherapy consisting of pirarubicin (25 mg/m2/d for 2 days), cytarabine (100 mg/m2/d for 7 days), and etoposide (150 mg/m2/d for 3 days)," scientists in Tsukuba, Japan report.

"Patients received four courses of intensification therapy of the same regimen. Prophylaxis for CNS leukemia was not included. All but two patients were younger than 4 years, and 67 of the 72...


Source: Cancer Weekly (2008-04-29)

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