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Acute Myeloid Leukemia
Study results from University of Calcutta provide new insights into acute myeloid leukemia
April 29th, 2008
"The objective of the paper was to study the association of polymorphisms of phases 1 and 11 xenobiotic metabolizing enzyme genes cytochrome P450 (CYP-4501 Al *2A, *2B, *2C and *4 alleles, CYP-4502D6*4 allele), glutathione-S-transferase (GSTM1 and GSTT1 null genotypes) and N-acetyl transferase 2 (NAT2*613 and *7A alleles) with the incidence of acute myeloid leukemia (AML) in an eastern Indian population. Polymerase chain reaction and restriction fragment length polymorphism of genomic DNA from peripheral blood cells were used to detect CYP-450 and NAT2 gene polymorphisms in 110 AM L patients and 144 racially and geographically matched normal controls," scientists writing in the European...
Source: Cancer Weekly (2008-04-29)
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