Cancer Weekly
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Apoptosis
Researchers at Johns Hopkins University have published new data on apoptosis
April 29th, 2008
According to recent research from the United States, "Microscopic findings associated with paclitaxel (Taxol) chemotherapy toxicity were described years ago but whether they are specific for toxicity remains unclear. Further, epithelial changes associated with taxanes can mimic high-grade dysplasia (HGD) in non-neoplastic gastrointestinal (GI) tract mucosa." "Similar changes associated with colchicine are only seen in patients with toxicity. GI tract specimens were reviewed (221 total; 93 esophageal, 55 gastric cardiac, 48 oxyntic, 7 antral, 8 small bowel, 6 colonic, 3 appendiceal, 1 anal) from 71 patients (63M, 817), 38 to 84 years (median, 55 y) undergoing...
Source: Cancer Weekly (2008-04-29)
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