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Falciparum Malaria
Data on falciparum malaria detailed by researchers at University of Melbourne, Department of Medicine
May 6th, 2008
Fresh data on falciparum malaria are presented in the report 'Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line.' According to recent research from Australia, "Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 family member, termed VAR2CSA." "VAR2CSA appears to be the main ligand responsible for adhesion to chondroitin sulphate A (CSA). Whether other PfEMP1 molecules can also mediate placental adhesion, independent of...
Source: Cancer Weekly (2008-05-06)
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