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Cancer Gene Therapy
Kyushu University reports research in cancer gene therapy
May 6th, 2008
According to recent research from Fukuoka, Japan, "Adenovirus-mediated gene therapy combined with radiation is expected to be a new approach to treat pancreatic cancer. However, there are no reports of definitive effects of radiation on adenovirus-mediated gene therapies." "In the present study, we investigated the effect of radiation on the transduction efficiency of an adenovirus-based gene therapy. We used adenovirus expressing NK4 (Ad-NK4), an antagonist for hepatocyte growth factor, as a representative gene therapy. Pancreatic cancer cells preinfected with Ad-NK4 were irradiated, and NK4 levels in culture media of these cells were measured. We investigated...
Source: Cancer Weekly (2008-05-06)
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