Cancer Weekly
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Ataxia Telangiectasia
Research results from University College update understanding of ataxia telangiectasia
May 6th, 2008
According to recent research from London, the United Kingdom, "Premature or stress-induced senescence is a major cellular response to chemotherapy in solid tumors and contributes to successful treatment. However, senescent tumor cells are resistant to apoptosis and may also reenter the cell cycle." "We set out to find a means to specifically induce senescent tumor cells to undergo cell death and not to reenter the cell cycle that may have general application in cancer therapy. We investigated the mechanisms regulating cell survival in drug-induced senescent tumor cells. Using immunofluorescence and flow cytometry-based techniques, we established the status of the ataxia...
Source: Cancer Weekly (2008-05-06)
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