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Cancer Weekly

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B-Cell Lymphoma



Research on B-cell lymphoma discussed by scientists at Kinki University, Medical Department



May 6th, 2008

According to a study from Osaka, Japan, "Age-related Epstein-Barr virus-positive (EBV+) B-cell lymphoproliferative disorder (ALPD) is a disease entity identified from a large-scale re-survey of cases diagnosed as diffuse large B-cell lymphoma. ALPD is a group of EBV+ polymorphic B-cell lymphoma typically seen in elderly patients."

"An age-associated decline in host immunity against EBV might be partly responsible for the pathogenesis of ALPD. Histologically, ALPD is often characterized by a minor proportion of EBV-encoded RNA-positive tumor cells in a background of extensive cellular infiltration, similar to that of classical Hodgkin's lymphoma. In contrast to Hodgkin...


Source: Cancer Weekly (2008-05-06)

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