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Cancer Gene Therapy
Chonbuk National University, National University Medical School publishes research in cancer gene therapy
May 13th, 2008
Research findings, 'Adenovirus-mediated expression of dominant negative c-myb induces apoptosis in head and neck cancer cells and inhibits tumor growth in animal model,' are discussed in a new report. According to a study from Korea, "The recent demonstration of aberrant expression of the c-myb proto-oncogene in various cancers suggests that c-myb plays an important role in the development of cancer. On this basis, it has been proposed that ablation of c-myb function might be an effective approach for therapy of c-myb dependent malignancies." "We previously used a dominant negative c-myb (DN-myb) construct to induce apoptosis in K562 cells. In this study, DN-myb was...
Source: Cancer Weekly (2008-05-13)
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