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Cancer Gene Therapy
Research reports on cancer gene therapy from University of Liege provide new insights
May 13th, 2008
Scientists discuss in 'The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors' new findings in cancer gene therapy. According to recent research from Liege, Belgium, "Overexpression of the ERBB2 oncogene is observed in about 20% of human breast tumors and is the consequence of increased transcription rates frequently associated with gene amplification. Several studies have shown a link between activator protein 2 (AP-2) transcription factors and ERBB2 gene expression in breast cancer cell lines." "Moreover, the Yin Yang 1 (YY1) transcription factor has been shown to stimulate AP-2...
Source: Cancer Weekly (2008-05-13)
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