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Cancer Weekly

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Cancer Vaccines



Studies by F. Botta and co-authors describe new findings in cancer vaccines



May 13th, 2008

Investigators publish new data in the report 'Adrenergic modulation of dendritic cell cancer vaccine in a mouse model: role of dendritic cell maturation.' "The aim of the present study was to evaluate the role of beta2-adrenergic receptors (beta2-ARs) in the outcome of a dendritic cell (DC)-based cancer vaccine in the murine E.G7-ovalbumin (OVA) model. We found that unlike the beta2-AR expressed on antigen loaded DCs, beta2-ARs expressed in the site of DCs inoculation may influence the efficacy of the antitumor response," scientists in Locarno, Switzerland report.

"Intradermal injection of Staphylococcus aureus peptidoglycan along with the beta2-AR-specific...


Source: Cancer Weekly (2008-05-13)

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