Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Immunization
Scientists at University of Miami, Sylvester Comprehensive Cancer Center describe research in immunization
May 13th, 2008
Research findings, 'Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells,' are discussed in a new report. "Tumor-induced immune suppression is one of the most difficult obstacles to the success of tumor immunotherapy. Here, we show that established tumors suppress CD8 T cell clonal expansion in vivo, which is normally observed in tumor-free mice upon antigen-specific glycoprotein (gp) 96-chaperone vaccination," investigators in the United States report. "Suppression of CD8 T-cell expansion by established tumors is independent of tumor-associated expression of the antigen that is recognized by the CD8-T-cell...
Source: Cancer Weekly (2008-05-13)
|
