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Cancer Weekly

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Melanoma Vaccines



Data on melanoma vaccines discussed by researchers at H. Lee Moffitt Cancer Center



May 13th, 2008

A report, 'Nonmyeloablative chemotherapy followed by T-cell adoptive transfer and dendritic cell-based vaccination results in rejection of established melanoma,' is newly published data in Journal of Immunotherapy. According to a study from the United States, "We demonstrated previously that dendritic cell (DC)-based vaccines could mediate a specific and long-lasting antitumor immune response during early lymphoid reconstitution after lethal irradiation and bone marrow transplant. The purpose of this current study was to examine the potential therapeutic efficacy of DC-based vaccines in combination with sublethal lymphodepletion and T-cell transfer."

"In an...


Source: Cancer Weekly (2008-05-13)

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