Cancer Vaccines

Research on cancer vaccines described by D. Atanackovic and colleagues

Published in Cancer Weekly, May 13th, 2008

According to a study from the United States, "We previously reported results of a phase II trial in which recombinant MAGE-A3 protein was administered with or without adjuvant AS02B to 18 non-small-cell lung cancer (NSCLC) patients after tumor resection. We found that the presence of adjuvant was essential for the development of humoral and cellular responses against selected MAGE-A3 epitopes."

"In our current study, 14 patients that still had no evidence of disease up to 3 years after vaccination with MAGE-A3 protein with or without adjuvant received an additional four doses of MAGE-A3 protein with adjuvant AS02B. After just one boost injection, six of seven patients...

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Source: Cancer Weekly (2008-05-13)

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