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Cancer Weekly

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B-Cell Lymphoma



University of Miami reports research in B-cell lymphoma



May 13th, 2008

" The heterogeneity of diffuse large B-cell lymphoma (DLBCL) has prompted the search for new markers that can accurately separate prognostic risk groups. We previously showed in a multivariate model that LMO2 mRNA was a strong predictor of superior outcome in DLBCL patients," researchers in the United States report.

"Here, we tested the prognostic impact of LMO2 protein expression in DLBCL patients treated with anthracycline-based chemotherapy with or without rituximab. Patients and Methods DLBCL patients treated with anthracycline-based chemotherapy alone ( 263 patients) or with the addition of rituximab ( 80 patients) were studied using immunohistochemistry for LMO2...


Source: Cancer Weekly (2008-05-13)

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