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Cancer Vaccines



Research reports on cancer vaccines from E.N. Vinageras and colleagues provide new insights



May 13th, 2008

" We show the result of a randomized phase II clinical trial with an epidermal growth factor (EGF)-based cancer vaccine in advanced non-small-cell lung cancer (NSCLC) patients, evaluating immunogenicity, safety, and effect on survival. Patients and Methods Eighty patients with stage IIIB/IV NSCLC after finishing first-line chemotherapy were randomly assigned to receive best supportive care or EGF vaccinations," scientists in Havana, Cuba report.

" Vaccination was safe. Adverse events were observed in less than 25% of cases and were grade 1 or 2 according to National Cancer Institute Common Toxicity Criteria. Good anti-EGF antibody response (GAR) was obtained in 51.3% of...


Source: Cancer Weekly (2008-05-13)