Cancer Weekly
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Breast Cancer
Data on breast cancer described by T.E. Delea et al
May 13th, 2008
" In the primary core analysis of BIG 1-98, a randomized, double-blind trial comparing 5 years of initial adjuvant therapy with letrozole versus tamoxifen in postmenopausal women with hormone receptor-positive (HR+) early breast cancer, letrozole significantly improved disease-free survival by 19% and reduced the risk of breast cancer recurrence by 28% and distant recurrence by 27%. A Markov model was used to estimate the incremental cost per quality-adjusted life year (QALY) gained with 5 years of initial adjuvant therapy with letrozole versus tamoxifen from a Canadian healthcare system perspective," scientists writing in the journal Breast Cancer Research and Treatment...
Source: Cancer Weekly (2008-05-13)
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