Physiology
Findings in physiology reported from University of Kansas
Published in Cancer Weekly, May 13th, 2008
New investigation results, 'Effects of Muclin (Dmbt1) deficiency on the gastrointestinal system,' are detailed in a study published in American Journal of Physiology - Gastrointestinal and Liver Physiology. According to a study from the United States, "The Dmbt1 gene encodes alternatively spliced glycoproteins that are either membrane-associated or secreted epithelial products. Functions proposed for Dmbt1 include it being a tumor suppressor, having roles in innate immune defense and inflammation, and being a Golgi-sorting receptor in the exocrine pancreas."
"The heavily sulfated membrane glycoprotein mucin-like glycoprotein (Muclin) is a Dmbt1 product that is...
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Source: Cancer Weekly (2008-05-13)
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