Cancer Weekly
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Cancer Gene Therapy
Studies from Hokkaido University, Faculty of Pharmaceutical Sciences add new findings in the area of cancer gene therapy
May 20th, 2008
New research, 'Post-transcriptional regulation of breast cancer resistance protein after intestinal ischemia-reperfusion,' is the subject of a report. According to recent research from Sapporo, Japan, "Breast cancer resistance protein (BCRP), the product of the ABCG2 gene, is a recently identified ATP binding cassette half-transporter. BCRP is expressed in a variety of tumor cells and many normal human tissues." "In the small intestine, BCRP can limit the influx and facilitate the efflux to prevent intracellular accumulation of BCRP substrates. Ischemia-reperfusion (I/R) induces the release of reactive oxygen species, and organs are severely damaged by I/R. It has been...
Source: Cancer Weekly (2008-05-20)
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