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Cancer Weekly

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Cancer Gene Therapy



Studies from University College, Department of Computer Science provide new data on cancer gene therapy



May 20th, 2008

A report, 'The in vivo rate of somatic adenomatous polyposis coli mutation,' is newly published data in American Journal of Pathology. "Cancer arises through successive somatic mutations/epimutations of oncogenes and tumor-suppressor genes. Accurate estimates of the rates at which these (epi)mutations occur are a vital but missing link in our emerging quantitative understanding of tumorigenesis," researchers in London, the United Kingdom report.

"Their absence has hindered arguments concerning the importance of genetic instability in tumorigenesis and the number of mutations that precede malignant conversion of healthy cell lineages. Herein, a novel method for...


Source: Cancer Weekly (2008-05-20)

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