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Gene Therapy
Research on gene therapy published by scientists at University of Tennessee, Health Science Center
May 20th, 2008
Scientists discuss in 'The block to membrane fusion differs with the site of ligand insertion in modified retroviral envelope proteins' new findings in gene therapy. According to recent research from the United States, "Efforts to achieve cell type-specific transduction of retroviral vectors for gene therapy have centred on modification of the envelope protein (Env). Typically, addition of a ligand to Env gives binding to the new or target receptor, but little or no infection, and affects the subunit association of the modified Env." "We previously discovered two point mutations that increase targeted infection by over 1000-fold when added to an Env modified by...
Source: Cancer Weekly (2008-05-20)
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