Cancer Weekly
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Actinic Keratosis
New actinic keratosis study results from Henry Ford Hospital described
May 20th, 2008
According to recent research from the United States, "Actinic keratosis (AK) and Bowen's disease (BD) are common patterns of in situ squamous cell carcinoma of the epidermis. In AK, atypical keratinocytes proliferate in the lower portion of the epidermis including the basal layer." "In contrast, BD features' atypical squamous cells in all portions of the epidermis but initially leaves basal cells in palisades along the basement membrane. To characterize immunohistochemically keratocyte proliferation in AK and Palisading Basal Cells (PBC) in BD, we stained microarray samples of 45 AK and 25 BD with Molecular Immunology Borstel (MIB-1). Subsequent inummostaining of full...
Source: Cancer Weekly (2008-05-20)
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