Cancer Weekly
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Anesthesia
Recent findings from B.H. Ko and co-authors highlight research in anesthesia
May 20th, 2008
According to recent research published in the European Journal of Nuclear Medicine and Molecular Imaging, " Small animal imaging with meta-iodobenzylguanidine (MIBG) allows characterization of animal models, optimization of tumor treatment strategies, and monitoring of gene expression. Anesthetic agents, however, can affect norepinephrine (NE) transport and systemic sympathetic activity." "We thus elucidated the effects of anesthetic agents on MIBG transport and biodistribution. SK-N-SH neuroblastoma and PC-12 pheochromocytoma cells were measured for I-123-MIBG uptake after treatment with ketamine (Ke), xylazine (Xy), Ke/Xy, or pentobarbital (Pb). NE...
Source: Cancer Weekly (2008-05-20)
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