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DNA Research

Report summarizes DNA research study findings from University of Texas, Department of Radiation Oncology

Published in Cancer Weekly, May 20th, 2008

A report, 'Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts,' is newly published data in Radiation Research. "DNA damage generated by high-energy and high-Z (HZE) particles is more skewed toward multiply damaged sites or clustered DNA damage than damage induced by low-linear energy transfer (LET) X and gamma rays. Clustered DNA damage includes abasic sites, base damages and single-(SSBs) and double-strand breaks (DSBs)," scientists in the United States report.

"This complex DNA damage is difficult to repair and may require coordinated recruitment of multiple DNA repair factors. As a consequence of the production of irreparable...

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