Ovarian Cancer
Research conducted at Center for Radiopharmaceutical Science has updated our knowledge about ovarian cancer
Published in Cancer Weekly, May 20th, 2008
A new study, 'Antibodies directed against L1-CAM synergize with Genistein in inhibiting growth and survival pathways in SKOV3ip human ovarian cancer cells,' is now available. "Antibodies directed against the L1 cell adhesion protein inhibit growth of SKOV3ip human ovarian cancer cells in vitro and in vivo. Responses of SKOV3ip cells in vitro to anti-L1 mAb chCE7 and Genistein were investigated," scientists writing in the journal Cancer Letters report.
"Genistein potentiated the anti-proliferative and pro-apoptotic effects of chCE7 in SKOV3ip cells. A combination of mAb chCE7 and Genistein strongly reduced the sensitivity of p44/42 (Erk1,2) kinase, Src kinase and...
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Source: Cancer Weekly (2008-05-20)
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