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Cancer Weekly

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Cancer Gene Therapy



Data on cancer gene therapy published by researchers at Institute of Immunology and Experimental Therapy



May 20th, 2008

Data detailed in 'Liposomal formulation of 5-fluorocytosine in suicide gene therapy with cytosine deaminase--for colorectal cancer' have been presented. According to recent research published in the journal Cancer Letters, "It is generally accepted that successful gene therapy depends on two major factors: tumor-specific expression of a therapeutic gene and the efficient transfer of a therapeutic gene to tumor cells. For gene-directed enzyme prodrug therapy (GDEPT) involving Escherichia coli cytosine deaminase (CD) and 5-fluorocytosine (5-FC), several tumor-specific promoters and virus-based vectors were used."

"No attention whatsoever was paid to the way...


Source: Cancer Weekly (2008-05-20)

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