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Cancer Gene Therapy
Studies from Seoul National University have provided new information about cancer gene therapy
May 27th, 2008
"The low efficiency of conventional therapies in achieving long-term survival of lung cancer patients calls for development of novel options. Revisiting of aerosol gene delivery may provide an alternative for safe and effective treatment for lung cancer," scientists writing in the journal Cancer Gene Therapy report. "In this study, imidazole ring-containing urocanic acid-modified chitosan (UAC) designed in the previous study was used as a gene carrier. The potential effects of phosphatase and tensin homolog deleted on chromosome 10 ( PTEN) on Akt-related signals and cell cycle regulation were evaluated. Aerosols of UAC-PTEN were delivered into K-ras(LA1) lung...
Source: Cancer Weekly (2008-05-27)
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