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Cancer Weekly

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Cancer Vaccines



Research by N. Mottet and colleagues in cancer vaccines provides new insights



May 27th, 2008

According to recent research from France, "The hormone-refractory status is defined in a confirmed castrated man (who stopped any antiandrogen 6 wk earlier) by three consecutive prostate-specific antigen (PSA) increases above the nadir, reaching at least more than 50% of the nadir. It is standard of care to continue androgen-deprivation therapy (ADT) at this time."

"Two randomized phase 3 trials have demonstrated a survival benefit of 2 mo using a 3-wk docetaxel regimen, with a follow up of more than 50 mo. The decision for an immediate or a symptom-triggered-delayed chemotherapy must be tailored on the basis of prognostic factors such as a high PSA level, a short PSA...


Source: Cancer Weekly (2008-05-27)

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