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Cancer Gene Therapy
Findings in cancer gene therapy reported from Leiden University, Department of Pathology
May 27th, 2008
New investigation results, 'ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism,' are detailed in a study published in BMC Cancer. According to a study from Leiden, Netherlands, "Loss of heterozygosity (LOH) at chromosome arm 16q is frequently observed in human breast cancer, suggesting that one or more target tumor suppressor genes (TSGs) are located there. However, detailed mapping of the smallest region of LOH has not yet resulted in the identification of a TSG at 16q." "Therefore, the present study attempted to identify TSGs using an...
Source: Cancer Weekly (2008-05-27)
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