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Cancer Gene Therapy
Seoul National University, College of Pharmacy details research in cancer gene therapy
May 27th, 2008
A report, 'Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells,' is newly published data in European Journal of Pharmaceutics and Biopharmaceutics. "Mutations in the p53 tumor suppressor gene are the most common molecular genetic abnormalities to be described in lung cancer. However, there have been few reports of nonviral vector-mediated p53 gene delivery in lung cancer," researchers in Seoul, Korea report. "A new formulation of cationic solid lipid nanoparticles (SLNs) for gene delivery was produced by the melt homogenization method with slight modification, and the SLNs were formulated by mixing tricaprin (TC) as a core,...
Source: Cancer Weekly (2008-05-27)
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