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Adenoma
Findings from University of Genoa broaden understanding of adenoma
May 27th, 2008
According to recent research published in the Journal of Clinical Endocrinology & Metabolism, "Objective and Patients: Twenty-four pituitary adenomas from acromegalic patients (13 females, 11 males; age range 19-65 yr) were characterized for somatostatin receptor subtype 2A (sst(2A)), dopamine D-2 receptor (D2R), GH, and prolactin (PRL) expression by immunohistochemistry, and results correlated with the in vitro and in vivo hormone responses to octreotide and quinagolide. In nine cases, GH and PRL content was further studied by immunoelectron microscopy." "Immunoreactivity was semiquantitatively scored as 2 (> 50% stained cells), 1 (10-50% stained cells), and...
Source: Cancer Weekly (2008-05-27)
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