Cancer Weekly
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Ampullary Cancer
Study data from Juntendo University, Medical Department update understanding of ampullary cancer
May 27th, 2008
"Glands near the surface of the papilla of Vater may become distended with mucus and become hyperplastic; that is, become distended. In this study, we tried to clarify carcinogenesis in these distended glands," investigators in Hongo, Japan report. "Twenty-nine pancreatoduodenectomized nontumorous duodenal papilla specimens from carcinoma of the pancreas and bile duct and 34 resected ampullary carcinoma specimens were studied histopathologically and immunohistochemically, using cytokeratins and mucin immunohistochemical features/phenotypes. Distended glands were found in 11 of the 29 pancreatoduodenectomized specimens. These glands were immunopositive for cytokeratin...
Source: Cancer Weekly (2008-05-27)
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