Cancer Weekly
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Angiogenesis
Research from W. Huang and co-researchers in the area of angiogenesis published
May 27th, 2008
According to recent research from Shanghai, People's Republic of China, "Angiotensin II (Ang II) has been reported to promote tumor progression, tumor growth and angiogenesis in many cancers. We previously observed that angiotensin II type1 receptors (AT1R) were upregulated in human gastric cancer and may be involved in the progression of gastric cancer." "We studied the effects of AT1R antagonist on angiogenesis and growth in gastric cancer xenografts to observe the mechanism action of AT1R in the gastric cancer. The results showed that the growth of gastric cancer cells was significantly suppressed by treatment with AT1R antagonist. In vivo, TCV-116, at doses of both...
Source: Cancer Weekly (2008-05-27)
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