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Cancer Weekly

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Cancer Gene Therapy



Osaka University publishes research in cancer gene therapy



June 3rd, 2008

Research findings, 'Development of PEGylated adenovirus vector with targeting ligand,' are discussed in a new report. According to a study from Suita, Japan, "For effective gene therapy, a vector system that transduces the therapeutic gene into target cells efficiently and safely is essential. Adenovirus (Ad) vectors frequently are used for gene therapy research, especially cancer gene therapy, because of their high transduction efficiency."

"However, broad clinical utility of Ad vectors have not yet been achieved owing to problems related to several properties inherent to Ads. Systemic administration of Ad vectors leads to acute virus accumulation and undesirable...


Source: Cancer Weekly (2008-06-03)

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