Cancer Weekly
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Cancer Gene Therapy
Reports outline cancer gene therapy study results from University of Maryland
June 3rd, 2008
A new study, 'Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis,' is now available. "A common element among cancer cells is the presence of improperly controlled transcription. In these cells, the degree of specific activation of some genes is abnormal, and altering the aberrant transcription may therefore directly target cancer," scientists in the United States report. "TFIIS is a transcription elongation factor, which directly binds the transcription motor, RNA Polymerase II and allows it to read through various transcription arrest sites. We report on RNA interference of TFIIS, a transcription elongation factor, and its...
Source: Cancer Weekly (2008-06-03)
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