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Cancer Weekly

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DNA Research



Research conducted at University of Tubingen, Department of Radiation Oncology has provided new information about DNA research



June 3rd, 2008

Fresh data on dna research are presented in the report 'Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation.' In this recent report, researchers in Germany conducted a study "To elucidate the interaction between radioprotector O-phospho-l-tyrosine (P-Tyr) with epidermal growth factor receptor (EGFR). Molecular effects of P-Tyr at the level of EGFR responses were investigated in vitro with TP53-wildtype bronchial carcinoma cell line A549, which is radio-protected by P-Tyr treatment."

"Nuclear EGFR accumulation was followed by confocal microscopy and Western blotting. PKCepsilon protein expression was...


Source: Cancer Weekly (2008-06-03)

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